Premedication Protocol for Iodine Contrast Allergy

If the patient’s previous contrast reaction was severe and involved difficulty breathing, facial or neck swelling, or hospitalization; consult with one of the radiologist before scheduling the exam.

For a history of mild to moderate reactions:

  • Prednisone – 50mg by mouth at 13 hours, 7 hours, and 1 hour before contrast injection.
  • Benadryl – 50mg by mouth, IV, or intramuscular at 1 hour before contrast injection.